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Monday, February 9, 2009

U.S. Army Lab Freezes Research on Dangerous Pathogens Due to Unaccounted High-Risk Microbes and Biomaterials

The U.S. Army Medical Research Institute of Infectious Diseases (USAMRIID) has suspended research activities involving biological select agents and toxins. Army officials took the step on Friday after discovering apparent problems with the system of accounting for high-risk microbes and biomaterials at the Fort Detrick, Maryland, facility.

The lab has been under intense scrutiny since August, when the Federal Bureau of Investigation (FBI) named former USAMRIID researcher Bruce Ivins as the perpetrator of the 2001 anthrax letter attacks. Although the case never went to trial because of Ivins's suicide on 29 July 2008, FBI officials have claimed that the evidence against him is indisputable and that he carried out the mailings using anthrax stolen from a flask at USAMRIID.

Officials have begun a complete inventory of all select agents and toxins at the facility. All experiments using select agents will remain suspended until the accounting is finished, which could take several weeks. Several USAMRIID researchers have been grumbling about the decision, which seems to have caught them by surprise, according to a government official not connected to the lab.

The decision was announced by institute commander Col. John Skvorak in a 4 February memo to employees. The memo, which ScienceInsider has obtained, says the standard of accountability that USAMRIID had been applying to its select agents and toxins was not in line with the standard required by the Army and the Department of Defense. USAMRIID officials believed that a satisfactory accounting involved finding all the items listed on its database; the Army and DOD wanted the converse—that is, all select agents and toxins needed to be matched to the database.

According to the memo, any materials found without a corresponding record in the database must be reported to the Vice Chief of Staff of the Army. "I believe that the probability that there are additional vials of BSAT [biological select agents and toxins] not captured in our … database is high," Skvorak wrote.

A former USAMRIID scientist told ScienceInsider that in the past, inventorying of biological materials at the institute routinely turned up items that had not been listed on the database before. Those items would be added to the database without shutting down research.

—Yudhijit Bhattacharjee

http://blogs.sciencemag.org/scienceinsider/2009/02/us-army-lab-fre-1.html

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